Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ucf-101 (Standard)

Ucf-101 (Standard) is the analytical standard of Ucf-101. This product is intended for research and analytical applications. Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2, with an IC50 of 9.5 μM for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC50>200 μM) . Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect[1][2][3].

Product Specifications

CAS Number

313649-08-0

UNSPSC

12352100

Target

Apoptosis; Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Neurological Disease; Cardiovascular Disease

Smiles

O=C(/C(C(N1C2=CC=CC=C2)=O)=C/C3=CC=C(C4=C([N+]([O-])=O)C=CC=C4)O3)N(C5=CC=CC=C5)C1=S

Molecular Formula

C27H17N3O5S

Molecular Weight

495.51

References & Citations

[1]Cilenti L, et, al. Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2. J Biol Chem. 2003 Mar 28;278 (13) :11489-94.|[2]Liu HR, et, al. Role of Omi/HtrA2 in apoptotic cell death after myocardial ischemia and reperfusion. Circulation. 2005 Jan 4;111 (1) :90-6.|[3]Li Y, et, al. Ucf-101 protects in vivoandin vitro models of PD against 6-hydroxydopamine toxicity by alleviating endoplasmic reticulum stress via the Wnt/β-catenin pathway. J Clin Neurosci. 2020 Jan;71:217-225.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

LUCS® 13, green fluorescent nucleic acid stain, 1 mL, 5 mM/DMSO
44010 1 mL

LUCS® 13, green fluorescent nucleic acid stain, 1 mL, 5 mM/DMSO

Sign In for Pricing
View Details
VEGF Receptor 2 (KDR) (NM_002253) Human Recombinant Protein
TP710249 20 µg

VEGF Receptor 2 (KDR) (NM_002253) Human Recombinant Protein

Sign In for Pricing
View Details
BMP3 Rabbit pAb
E2160090 100 µL

BMP3 Rabbit pAb

Sign In for Pricing
View Details
RPIP8 (RUNDC3A) (NM_006695) Human Recombinant Protein
TP300211L 1 mg

RPIP8 (RUNDC3A) (NM_006695) Human Recombinant Protein

Sign In for Pricing
View Details
SCRG1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
43200061 1.0 µg DNA

SCRG1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

Sign In for Pricing
View Details
RNF40 antibody
MBS9406350-01 0.05 mL

RNF40 antibody

Sign In for Pricing
View Details