Uridine diphosphate glucuronic acid-13C,15N2

Uridine diphosphate glucuronic acid-13C,15N2 (UDP-α-D-glucuronic acid-13C,15N2) is the 13C- and 15N-labeled Uridine diphosphate glucuronic acid (HY-125954) . Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum[1][2].

Product Specifications

Product Name Alternative

UDP-α-D-glucuronic acid-13C,15N2

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O=C(C=C[15N]1[C@@H]2O[C@@H]([C@H]([C@H]2O)O)COP(O)(OP(O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O)(O)=O)=O)[15NH][13C]1=O

Molecular Formula

C14 13CH22 15N2O18P2

Molecular Weight

583.26

References & Citations

[1]Annika J E Borg, et al. Mechanistic characterization of UDP-glucuronic acid 4-epimerase. FEBS J. 2021 Feb;288 (4) :1163-1178.|[2]DUTTON GJ. Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides. Biochem J. 1956 Dec;64 (4) :693-701.