(22R) -Budesonide-d6
(22R) -Budesonide-d6 (Dexbudesonide-d6) is deuterium labeled (22R) -Budesonide. (22R) -Budesonide ((22R) -BUD) is the (22R) -enantiomer of Budesonide. (22R) -Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity[1].
Product Specifications
Product Name Alternative
Dexbudesonide-d6; (22R) -BUD-d6
UNSPSC
12352005
Target
Drug Isomer; Glucocorticoid Receptor; Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Others; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
C[C@@]12[C@@]3(C(C([2H])([2H])O)=O)[C@@](O[C@H](O3)CCC)([H])C[C@@]1([H])[C@]4([H])CC([2H])([2H])C5=C([2H])C(C([2H])=C[C@]5(C)[C@@]4([H])[C@@H](O)C2)=O
Molecular Formula
C25H28D6O6
Molecular Weight
436.57
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Youming Lu, et al. Simultaneous quantification of 22R and 22S epimers of budesonide in human plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry: application in a stereoselective pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Mar 15:921-922:27-34.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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