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Myeloperoxidase, Human Neutrophil

Myeloperoxidase, Human Neutrophil is a peroxidase. Myeloperoxidase, Human Neutrophil is a potent antibacterial agent by catalyzing the H2O2-dependent oxidation of chloride anion to generate hypochlorous acid. Myeloperoxidase, Human Neutrophil catalyzes the degradation of N-retinyl-idene-N-retinylethanolamine, a toxic form of retinal lipofuscin. Myeloperoxidase, Human Neutrophil also triggers lysosomal stress and cell death. Myeloperoxidase, Human Neutrophil can be used for the researches of inflammation and infection[1].

Product Specifications

UNSPSC

12352211

Target

Bacterial; Glutathione Peroxidase

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Field of Research

Infection; Inflammation/Immunology

Smiles

[Myeloperoxidase,HumanNeutrophil]

References & Citations

[1]Yogalingam G, et al. Cellular Uptake and Delivery of Myeloperoxidase to Lysosomes Promote Lipofuscin Degradation and Lysosomal Stress in Retinal Cells. J Biol Chem. 2017 Mar 10;292 (10) :4255-4265.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Curated Selection

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