Isoapoptolidin
Isoapoptolidin is a mitochondrial F0F1-ATPase inhibitor (Ki>100 μM, selective for mitochondrial complex V) . Isoapoptolidin is promising for research of mitochondrial energy metabolism-related diseases (e.g., cancer, neurodegeneration) [1].
Product Specifications
CAS Number
476647-30-0
UNSPSC
12352005
Target
ATP Synthase; Mitochondrial Metabolism
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Field of Research
Cancer; Neurological Disease
Smiles
C/C1=C\C(C)=C\C(C)=C\[C@@H](C)[C@H](O[C@@H]2O[C@@H](C)[C@H](OC)[C@@H](O)[C@@H]2O)/C=C/C(C)=C/CC[C@H](O)[C@@H](OC)C[C@H](O)[C@H]([C@@]3(O)[C@H](C)[C@@H](O)[C@@H](C)[C@](C[C@@H](O[C@H]4C[C@](C)(O)[C@@H](O[C@@H]5O[C@H](C)[C@@H](O)[C@H](OC)C5)[C@H](C)O4)COC)([H])O3)OC1=O
Molecular Formula
C58H96O21
Molecular Weight
1129.37
References & Citations
[1]Pennington JD, et al. Toward a stable apoptolidin derivative: identification of isoapoptolidin and selective deglycosylation of apoptolidin. Org Lett. 2002 Oct 31;4 (22) :3823-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
