AL-34662 (formate)
AL-34662 (formate) is a 5-HT2 receptor agonist (IC50: 0.8-1.5 nM) . AL-34662 (formate) stimulates inositol phosphate turnover and Ca2+ release in human ciliary muscle cells (h-CM) (E50: 289 nM) and human trabecular meshwork cells (h-TM) (E50: 254 nM) . AL-34662 (formate) can be used in studies to lower intraocular pressure (IOP) [1].
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=CO.OC1=CC=C(C2=C1)C=NN2C[C@H](C)N
Molecular Formula
C11H15N3O3
Molecular Weight
237.26
References & Citations
[1]Sharif NA, et al. AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist. J Ocul Pharmacol Ther. 2007 Feb;23 (1) :1-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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