Tetragastrin
Tetragastrin (Cholecystokinin tetrapeptide; CCK-4) is the C-terminal tetrapeptide of gastrin. Tetragastrin can stimulate gastric secretion[1]. Tetragastrin is a Cholecystokinin (CCK-4) receptor agonist[2]. Gastric mucosal protection[3].
Product Specifications
CAS Number
1947-37-1
Product Name Alternative
Cholecystokinin tetrapeptide; CCK-4
UNSPSC
12352209
Target
Cholecystokinin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
99.89
Solubility
DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@@H](N)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O
Molecular Formula
C29H36N6O6S
Molecular Weight
596.70
References & Citations
[1]M Tatsuta, et al. Effect of 6-hydroxydopamine on gastric carcinogenesis and tetragastrin inhibition of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. Cancer Res. 1989 Aug 1;49 (15) :4199-203.|[2]A A Karelin, et al. Tetragastrin activation of rat gastric mucosa adenyl cyclase in vitro. Biull Eksp Biol Med. 1981 Apr;91 (4) :440-1.|[3]Nathalie Lara, et al. Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks. Neuropsychopharmacology. 2003 Oct;28 (10) :1840-5.|[4]Y Komuro, et al. Effects of tetragastrin on mucus glycoprotein in rat gastric mucosal protection. Gastroenterol Jpn. 1992 Oct;27 (5) :597-603.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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