IM176OUT05 (free base)
IM176OUT05 free base (2-Me-Phen), a biguanide, is a mitochondrial OXPHOS inhibitor. IM176OUT0 free base inhibits mitochondrial electron transport chain (ETC) activity with an IC50 of 3.2 μM. IM176OUT05 free base activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process[1].
Product Specifications
CAS Number
1544871-16-0
Product Name Alternative
2-Me-Phen; 2-Me-Phenformin
UNSPSC
12352005
Target
Mitochondrial Metabolism; Oxidative Phosphorylation
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
NC(NC(NCCC1=CC=CC=C1C)=N)=N
Molecular Formula
C11H17N5
Molecular Weight
219.29
References & Citations
[1]Son MJ, et al. A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming. Exp Mol Med. 2018 Dec 6;50 (12) :1-15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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