D159153
D159153 is a highly selective phosphodiesterase 4 (PDE4) inhibitor. D159153 is promising for research of asthma, chronic obstructive pulmonary disease (COPD), and neuroinflammatory disorders[1].
Product Specifications
CAS Number
[1158231-00-5]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(N)NC1=CC=C(CC2=CC=C(OC)C(C3=CC=CC([N+]([O-])=O)=C3)=C2F)C=C1
Molecular Formula
C21H18FN3O4
Molecular Weight
395.38
References & Citations
[1]Wunder F, et al. Characterization of the cellular activity of PDE 4 inhibitors using two novel PDE 4 reporter cell lines. Mol Pharm. 2013 Oct 7;10 (10) :3697-705.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125251/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4
Curated Selection
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