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D159153

D159153 is a highly selective phosphodiesterase 4 (PDE4) inhibitor. D159153 is promising for research of asthma, chronic obstructive pulmonary disease (COPD), and neuroinflammatory disorders[1].

Product Specifications

CAS Number

[1158231-00-5]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=C(N)NC1=CC=C(CC2=CC=C(OC)C(C3=CC=CC([N+]([O-])=O)=C3)=C2F)C=C1

Molecular Formula

C21H18FN3O4

Molecular Weight

395.38

References & Citations

[1]Wunder F, et al. Characterization of the cellular activity of PDE 4 inhibitors using two novel PDE 4 reporter cell lines. Mol Pharm. 2013 Oct 7;10 (10) :3697-705.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE4

Curated Selection

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