ULK-100
ULK-100 is a highly selective and potent ULK1 kinase inhibitor with an IC50 value of 1.6 nM. ULK-100 is promising for research of autophagy-related diseases (e.g., KRAS-mutant lung cancer, glioblastoma) [1].
Product Specifications
CAS Number
945377-65-1
UNSPSC
12352005
Target
ULK
Related Pathways
Autophagy
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(C1=CC(C2=C3N=CC(C4=CC=C(OCCN5CCCCC5)C=C4)=CN3N=C2)=CS1)N[C@@H](C(C)C)C(F)(F)F
Molecular Formula
C29H32F3N5O2S
Molecular Weight
571.66
References & Citations
[1]Martin KR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018 Oct 26;8:74-84.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ULK1
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4793906 1.0 µg DNA
Nipsnap3b sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details 
REPCB1029 1 mL
PCB 1x Element Congener PCB-74 100ug/mL in Isooctane - 1ML
Sign In for Pricing
View Details 