Nicardipine (Standard)
Nicardipine (Standard) is the analytical standard of Nicardipine. This product is intended for research and analytical applications. Nicardipine (YC-93 free base) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure[1].
Product Specifications
CAS Number
55985-32-5
UNSPSC
12352100
Target
Calcium Channel; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease; Cancer; Cardiovascular Disease
Smiles
O=C(C1=C(C)NC(C)=C(C(OCCN(C)CC2=CC=CC=C2)=O)C1C3=CC=CC([N+]([O-])=O)=C3)OC
Molecular Formula
C26H29N3O6
Molecular Weight
479.53
References & Citations
[1]Charnet P, et al. Electrophysiological analysis of the action of nifedipine and nicardipine on myocardial fibers. Fundam Clin Pharmacol. 1987;1 (6) :413-31.|[2]R Stamatiou, et al. The dihydropyridine calcium antagonist nicardipine reduces aortic smooth muscle cell viability, proliferation and migration. Cardiovascular Research, 2018 Apr,114 (1) :S43.|[3]Sherrin H. Baky. Nic ardipine Hydrochloride.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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