(R) - (-) -Chlorpheniramine (maleate)

(R) - (-) -Chlorpheniramine maleate is an enantiomer of Chlorpheniramine maleate (HY-B0286A) . Chlorpheniramine maleate is a H1 antihistamines. (R) - (-) -Chlorpheniramine maleate can be used for allergic diseases such as rhinitis and urticaria research[1][2].

Product Specifications

CAS Number

[23095-76-3]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Histamine Receptor

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Field of Research

Inflammation/Immunology

Smiles

OC(/C=C\C(O)=O)=O.CN(C)CC[C@@H](C1=CC=CC=N1)C2=CC=C(C=C2)Cl

Molecular Formula

C20H23ClN2O4

Molecular Weight

390.86

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Sakurai E, et al. The optical resolution of racemic chlorpheniramine and its stereoselective pharmacokinetics in rat plasma. J Pharm Pharmacol. 1992 Jan;44 (1) :44-7. |[2]Kim J, et al. Inhibitory effects of antihistamines, diphenhydramine and chlorpheniramine, on proton currents in BV2 microglial cells. Eur J Pharmacol. 2017 Mar 5;798:122-128.