SKF-86002 (Standard)
SKF-86002 (Standard) is the analytical standard of SKF-86002. This product is intended for research and analytical applications. SKF-86002 is an orally active p38 MAPK inhibitor, with anti-inflammatory, anti-arthritic and analgesic activities. SKF-86002 inhibits lipopolysaccharide (LPS) -stimulate human monocyte IL-1 and TNF-α production (IC50 = 1 μM) . SKF-86002 inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid[1][2][3].
Product Specifications
CAS Number
[72873-74-6]
UNSPSC
12352100
Target
P38 MAPK; Reference Standards
Related Pathways
MAPK/ERK Pathway; Others
Field of Research
Inflammation/Immunology
Smiles
FC1=CC=C(C2=C(C3=CC=NC=C3)N4C(SCC4)=N2)C=C1
Molecular Formula
C16H12FN3S
Molecular Weight
297.35
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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