Efonidipine (hydrochloride monoethanolate) (Standard)
Efonidipine (hydrochloride monoethanolate) (Standard) is the analytical standard of Efonidipine (hydrochloride monoethanolate) . This product is intended for research and analytical applications. 0
Product Specifications
CAS Number
111011-76-8
UNSPSC
12352100
Target
Calcium Channel; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Cardiovascular Disease
Smiles
CC1=C(P2(OCC(C)(C)CO2)=O)C(C3=CC([N+]([O-])=O)=CC=C3)C(C(OCCN(C4=CC=CC=C4)CC5=CC=CC=C5)=O)=C(C)N1.[H]Cl.CCO
Molecular Formula
C36H45ClN3O8P
Molecular Weight
714.18
References & Citations
[1]Ikeda K, et al. Efonidipine, a Ca (2+) -channel blocker, enhances the production of dehydroepiandrosterone sulfate in NCI-H295R human adrenocortical carcinoma cells. Tohoku J Exp Med. 2011;224 (4) :263-71.|[2]Nakano N, et al. Effects of efonidipine, an L- and T-type calcium channel blocker, on the renin-angiotensin-aldosterone system in chronic hemodialysis patients. Int Heart J. 2010 May;51 (3) :188-92.|[3]Suzuki S, et al. Beneficial effects of the dual L- and T-type Ca2+ channel blocker efonidipine on cardiomyopathic hamsters. Circ J. 2007 Dec;71 (12) :1970-6.|[4]Lee TS, et al. Actions of mibefradil, efonidipine and nifedipine block of recombinant T- and L-type Ca channels with distinct inhibitory mechanisms. Pharmacology. 2006;78 (1) :11-20.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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