NPD4456
NPD4456 (Compound 3) is a 3-phenylcoumarin Vpr inhibitor. NPD4456 binds to Vpr in a competitive manner. NPD4456 inhibits HIV-1 viral infection[1].
Product Specifications
CAS Number
859668-98-7
UNSPSC
12352005
Hazard Statement
H400
Target
HIV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(OC1=CC=C(C(O2)=C1)C(C)=C(C3=CC(OC)=CC=C3OC)C2=O)N(C)C
Molecular Formula
C21H21NO6
Molecular Weight
383.39
Precautions
P273-P391-P501
References & Citations
[1]Ong EB, et al. Vipirinin, a coumarin-based HIV-1 Vpr inhibitor, interacts with a hydrophobic region of VPR. J Biol Chem. 2011 Apr 22;286 (16) :14049-56.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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