BI 207524

BI 207524 is a selective non-nucleoside polymerase inhibitor targeting thumb pocket 1 of the HCV NS5B polymerase. BI 207524 exhibits antivirus activity. BI 207524 can be used for the research of infection, such as HCV infection[1].

Product Specifications

CAS Number

[874675-53-3]

UNSPSC

12352005

Target

HCV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(NC1(C(NC2=CC=C(/C=C/C(O)=O)C(OCC)=C2)=O)CCC1)C3=CC4=C(C=C3)C(C5CCCC5)=C(C6=NC=C(Cl)C=N6)N4C

Molecular Formula

C35H36ClN5O5

Molecular Weight

642.14

References & Citations

[1]Beaulieu PL, et al. Discovery of BI 207524, an indole diamide NS5B thumb pocket 1 inhibitor with improved potency for the potential treatment of chronic hepatitis C virus infection. J Med Chem. 2014 Dec 11;57 (23) :10130-43.