BC-54
BC-54 is a selective inhibitor of enzymes from the cAMP-specific PDE4 and PDE7 families. BC-54 displays potent anti-inflammatory properties and can induce cancer cells apoptosis. BC-54 can be used for the researches of cancer and inflammation, such as chronic lymphocytic leukemia[1].
Product Specifications
CAS Number
[534579-04-9]
UNSPSC
12352005
Target
Apoptosis; Phosphodiesterase (PDE)
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(C(/C(N1C2CCCCC2)=N\C(C)=O)=CC3=C1N=C(C=CC=C4)N4C3=O)OCC
Molecular Formula
C22H24N4O4
Molecular Weight
408.45
References & Citations
[1]de Medeiros AS, et al. Identification and characterization of a potent and biologically-active PDE4/7 inhibitor via fission yeast-based assays. Cell Signal. 2017 Dec;40:73-80.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4; PDE7
Curated Selection
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