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BC-54

BC-54 is a selective inhibitor of enzymes from the cAMP-specific PDE4 and PDE7 families. BC-54 displays potent anti-inflammatory properties and can induce cancer cells apoptosis. BC-54 can be used for the researches of cancer and inflammation, such as chronic lymphocytic leukemia[1].

Product Specifications

CAS Number

534579-04-9

UNSPSC

12352005

Target

Apoptosis; Phosphodiesterase (PDE)

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Field of Research

Cancer; Inflammation/Immunology

Smiles

O=C(C(/C(N1C2CCCCC2)=N\C(C)=O)=CC3=C1N=C(C=CC=C4)N4C3=O)OCC

Molecular Formula

C22H24N4O4

Molecular Weight

408.45

References & Citations

[1]de Medeiros AS, et al. Identification and characterization of a potent and biologically-active PDE4/7 inhibitor via fission yeast-based assays. Cell Signal. 2017 Dec;40:73-80.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE4; PDE7

Frequently Asked Questions

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