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FGI-106 (tetrahydrochloride)

FGI-106 tetrahydrochloride is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses. FGI-106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetrahydrochloride also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 nM and 150 nM, respectively[1].

Product Specifications

CAS Number

[1149348-10-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Dengue Virus; Flavivirus; HCV; HIV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Purity

98.74

Solubility

DMSO : 6.67 mg/mL (ultrasonic; warming; adjust pH to 2 with HCl; heat to 60°C)

Smiles

CC1=CC(NCCCN(C)C)=C2C=CC3=C4N=C(C)C=C(NCCCN(C)C)C4=CC=C3C2=N1.Cl.Cl.Cl.Cl

Molecular Formula

C28H42Cl4N6

Molecular Weight

604.49

Precautions

H302, H315, H319

References & Citations

[1]Aman MJ, et al. Development of a broad-spectrum antiviral with activity against Ebola virus. Antiviral Res. 2009 Sep;83 (3) :245-51.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HIV-1

Available Sizes

Curated Selection

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