Epiallopregnanolone-d5
Epiallopregnanolone-d5 (5α,3β-THDOC-d5) is deuterium labeled Epiallopregnanolone. Epiallopregnanolone (5α,3β-THDOC), a 3β-hydroxy neurosteroid, an antagonist at GABAA receptors and a NMDA receptor enhancer[1].
Product Specifications
Product Name Alternative
5α,3β-THDOC-d5
UNSPSC
12352211
Target
GABA Receptor; iGluR; Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
C[C@@]12[C@]([C@]3([H])CC[C@@]4([H])C([2H])([2H])[C@](O)([2H])C([2H])([2H])C[C@]4(C)[C@@]3([H])CC1)(CC[C@@H]2C(CO)=O)[H]
Molecular Formula
C21H29D5O3
Molecular Weight
339.52
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Brett C Ginsburg, et al. Alphaxalone and epiallopregnanolone in rats trained to discriminate ethanol. Alcohol Clin Exp Res. 2005 Sep;29 (9) :1621-9.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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