Dibromsalicil
Dibromsalicil (Compound 31) is a carboxylesterase (CES) inhibitor with activity of 72.7 nM against hiCE (human intestinal carboxylesterase) and 53.5 nM against rCE (rabbit liver carboxylesterase) . Dibromsalicil has almost no activity against hCE1 (human liver carboxylesterase) and cholinesterase[1].
Product Specifications
CAS Number
523-88-6
UNSPSC
12352005
Target
Carboxylesterase (CES)
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C(C(C1=CC(Br)=CC=C1O)=O)C2=CC(Br)=CC=C2O
Molecular Formula
C14H8Br2O4
Molecular Weight
400.02
References & Citations
[1]Wadkins RM, et al. Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases. J Med Chem. 2005 Apr 21;48 (8) :2906-15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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