4'-Hydroxytamoxifen (TFA) (Standard)
4'-Hydroxytamoxifen (TFA) (Standard) is the analytical standard of 4'-Hydroxytamoxifen (TFA) . This product is intended for research and analytical applications. 4'-Hydroxytamoxifen TFA is a salt form of a metabolite of Tamoxifen. 4'-Hydroxytamoxifen TFA has a higher affinity for ER than Tamoxifen. 4'-Hydroxytamoxifen TFA induces non-apoptotic cytotoxicity in human endometrial adenocarcinoma cells[1].
Product Specifications
UNSPSC
12352005
Target
Drug Metabolite; Estrogen Receptor/ERR; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
CC/C(C1=CC=C(C=C1)O)=C(C2=CC=C(C=C2)OCCN(C)C)\C3=CC=CC=C3.OC(C(F)(F)F)=O
Molecular Formula
C28H30F3NO4
Molecular Weight
501.54
References & Citations
[1]Cuevas M E, et al. In vitro cytotoxicity of 4'-OH-tamoxifen and estradiol in human endometrial adenocarcinoma cells HEC-1A and HEC-1B[J]. Oncology Reports, 2015, 33 (1) : 464-470.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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