J-104123
J-104123 is an inhibitor of squalene synthase with monocarboxylic acid structure. J-104123 can lower serum cholesterol level in dog models[1].
Product Specifications
CAS Number
[162037-54-9]
UNSPSC
12352005
Target
Farnesyl Transferase
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
O=C(C[C@@H](CC(N[C@@H](C)[C@H](/C=C/C1=CC=C2C=CC=CC2=C1)CC3=CC=C(C(Cl)=C3)Cl)=O)C)O
Molecular Formula
C28H29Cl2NO3
Molecular Weight
498.44
References & Citations
[1]Yoshikazu Iwasawa, et al (1996) . J-104,123, a novel and orally-active inhibitor of squalene synthase: Stereoselective synthesis and cholesterol lowering effects in dogs. Bioorganic & Medicinal Chemistry Letters 6 (4) 463-466.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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