SAR216471
SAR216471 is a P2Y12 receptor antagonist. SAR216471 reversibly blocks the binding of 2MeSADP to P2Y12 receptors in vitro with an IC50 of 17 nM. SAR216471 can result in the inhibition of platelet aggregation. SAR216471 exhibits anti-thrombotic activity in rat model. SAR216471 can be studied in research on thrombosis[1].
Product Specifications
CAS Number
1279867-21-8
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C(CCC)C1=C(C)N(C2=NN=C(NC(C3=CN(CC(N4CCN(C)CC4)=O)C5=C3C=C(Cl)C=C5)=O)C=C2)N=C1
Molecular Formula
C28H31ClN8O3
Molecular Weight
563.05
References & Citations
[1]Delesque-Touchard, N., et al., SAR216471, an alternative to the use of currently available P2Y₁₂ receptor inhibitors?. Thrombosis research, 134 (3), 693-703.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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