SAR216471

SAR216471 is a P2Y12 receptor antagonist. SAR216471 reversibly blocks the binding of 2MeSADP to P2Y12 receptors in vitro with an IC50 of 17 nM. SAR216471 can result in the inhibition of platelet aggregation. SAR216471 exhibits anti-thrombotic activity in rat model. SAR216471 can be studied in research on thrombosis[1].

Product Specifications

CAS Number

[1279867-21-8]

UNSPSC

12352005

Target

P2Y Receptor

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

O=C(CCC)C1=C(C)N(C2=NN=C(NC(C3=CN(CC(N4CCN(C)CC4)=O)C5=C3C=C(Cl)C=C5)=O)C=C2)N=C1

Molecular Formula

C28H31ClN8O3

Molecular Weight

563.05

References & Citations

[1]Delesque-Touchard, N., et al., SAR216471, an alternative to the use of currently available P2Y₁₂ receptor inhibitors?. Thrombosis research, 134 (3), 693-703.