ML389
ML389 is a highly selective vasopressin 1a (V1a) receptor antagonist (IC50=40 nM) . ML389 is promising for research of central nervous system disorders such as anxiety, depression, and post-traumatic stress disorder (PTSD) [1].
Product Specifications
CAS Number
1622294-25-0
UNSPSC
12352005
Target
Vasopressin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Smiles
O=C(C1CCN(C2=NC=C(Cl)C=C2)CC1)N(C3=CC=C(Cl)C=C3)CC4CC4
Molecular Formula
C21H23Cl2N3O
Molecular Weight
404.33
References & Citations
[1]Mittapalli G, et al. Optimization and characterization of an antagonist for vasopressin 1a (V1a) receptor. 2013 Dec 11 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD) : National Center for Biotechnology Information (US) ; 2010–.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
V1a Receptor
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