ML389

ML389 is a highly selective vasopressin 1a (V1a) receptor antagonist (IC50=40 nM) . ML389 is promising for research of central nervous system disorders such as anxiety, depression, and post-traumatic stress disorder (PTSD) [1].

Product Specifications

CAS Number

[1622294-25-0]

UNSPSC

12352005

Target

Vasopressin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease

Smiles

O=C(C1CCN(C2=NC=C(Cl)C=C2)CC1)N(C3=CC=C(Cl)C=C3)CC4CC4

Molecular Formula

C21H23Cl2N3O

Molecular Weight

404.33

References & Citations

[1]Mittapalli G, et al. Optimization and characterization of an antagonist for vasopressin 1a (V1a) receptor. 2013 Dec 11 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD) : National Center for Biotechnology Information (US) ; 2010–.