C14 Ceramide (d18:1/14:0) -d7

C14 Ceramide (d18:1/14:0) -d7 is the deuterium labeled C14 Ceramide (d18:1/14:0) (HY-124177A) . C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research[1][2].

Product Specifications

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Neurological Disease

Smiles

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(CCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O

Molecular Formula

C32H56D7NO3

Molecular Weight

516.89

References & Citations

[1]Oertel S, et al. Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity. Cell Mol Life Sci. 2017 Aug;74 (16) :3039-3055.|[2]Choi S, et al. Myristate-induced endoplasmic reticulum stress requires ceramide synthases 5/6 and generation of C14-ceramide in intestinal epithelial cells. FASEB J. 2018 Oct;32 (10) :5724-5736.