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FUB 465

FUB 465 is an orally active inverse agonist at the constitutively active histamine H3 receptor with a pKi of 6.2 for H3 receptor. FUB 465 can be used in the research of central nervous system diseases[1].

Product Specifications

CAS Number

184028-93-1

UNSPSC

12352005

Target

Histamine Receptor

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

N1=CNC(=C1)CCCOCC

Molecular Formula

C8H14N2O

Molecular Weight

154.21

References & Citations

[1]Meier G, et al. 4- (omega- (alkyloxy) alkyl) -1H-imidazole derivatives as histamine H (3) receptor antagonists/agonists. J Med Chem. 2004 May 6;47 (10) :2678-87.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

H3 Receptor

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