FUB 465
FUB 465 is an orally active inverse agonist at the constitutively active histamine H3 receptor with a pKi of 6.2 for H3 receptor. FUB 465 can be used in the research of central nervous system diseases[1].
Product Specifications
CAS Number
184028-93-1
UNSPSC
12352005
Target
Histamine Receptor
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
N1=CNC(=C1)CCCOCC
Molecular Formula
C8H14N2O
Molecular Weight
154.21
References & Citations
[1]Meier G, et al. 4- (omega- (alkyloxy) alkyl) -1H-imidazole derivatives as histamine H (3) receptor antagonists/agonists. J Med Chem. 2004 May 6;47 (10) :2678-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H3 Receptor
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