S-3448
S-3448 is a derivative of Ataciguat. S-3448 is a Soluble guanylate cyclase (sGC) agonist. S-3448 activates both the haem-containing and the haem-deficient form of sGC without depending on NO and heme. S-3448 can be used for cardiovascular diseases such as arterial hypertension and pulmonary hypertension research[1].
Product Specifications
CAS Number
254877-04-8
UNSPSC
12352005
Target
Guanylate Cyclase
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(NC1=CC=C(S(=O)(N2CCSCC2)=O)C=C1)C3=CC(OC)=C(OC)C=C3NS(=O)(C4=CC=C(Cl)C=C4)=O
Molecular Formula
C25H26ClN3O7S3
Molecular Weight
612.14
References & Citations
[1]Evgenov OV, et al. NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential. Nat Rev Drug Discov. 2006 Sep;5 (9) :755-68.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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