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S-3448

S-3448 is a derivative of Ataciguat. S-3448 is a Soluble guanylate cyclase (sGC) agonist. S-3448 activates both the haem-containing and the haem-deficient form of sGC without depending on NO and heme. S-3448 can be used for cardiovascular diseases such as arterial hypertension and pulmonary hypertension research[1].

Product Specifications

CAS Number

254877-04-8

UNSPSC

12352005

Target

Guanylate Cyclase

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

O=C(NC1=CC=C(S(=O)(N2CCSCC2)=O)C=C1)C3=CC(OC)=C(OC)C=C3NS(=O)(C4=CC=C(Cl)C=C4)=O

Molecular Formula

C25H26ClN3O7S3

Molecular Weight

612.14

References & Citations

[1]Evgenov OV, et al. NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential. Nat Rev Drug Discov. 2006 Sep;5 (9) :755-68.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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