ML 086
ML 086 is a highly selective PHOSPHO1 phosphatase inhibitor (IC50=0.14 μM) . ML 086 is promising for research of hereditary vascular calcification disorders (e.g., generalized arterial calcification of infancy) and spinal ligament ossification[1].
Product Specifications
CAS Number
1177148-36-5
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C(N(C)C)C1=CC=CC(N2SC3=C(C=CC=C3)C2=O)=C1
Molecular Formula
C16H14N2O2S
Molecular Weight
298.36
References & Citations
[1]Bravo Y, et al. Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. Bioorg Med Chem Lett. 2014 Sep 1;24 (17) :4308-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
JOT-EK0229Mo-01 48 Well
Mouse soluble interleukin-2 receptor,IL-2sRα ELISA KIT
Sign In for Pricing
View Details JOT-EK0229Mo-02 96 Well
Mouse soluble interleukin-2 receptor,IL-2sRα ELISA KIT
Sign In for Pricing
View Details MBS6411990-01 0.1 mL
Coagulation Factor XII (F12, HAF, HAE3, HAEX) (FITC)
Sign In for Pricing
View Details MBS6411990-02 5x 0.1 mL
Coagulation Factor XII (F12, HAF, HAE3, HAEX) (FITC)
Sign In for Pricing
View Details orb986808 100 µL
Phospho-CSK (Ser364) Rabbit Polyclonal Antibody (Cy3)
Sign In for Pricing
View Details