AS2575959 (sodium)

AS2575959 (sodium) is an agonist of GPR40. AS2575959 (sodium) can enhance glucose metabolism and has synergic effect with Sitagliptin (HY-13749) on insulin as well as incretin secretion. AS2575959 (sodium) can be studied in research on type 2 diabetes[1].

Product Specifications

CAS Number

[1616871-34-1]

UNSPSC

12352005

Target

Free Fatty Acid Receptor

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

O=C(O[Na])C[C@@H]1C2(CC2)OC3=CC(OCC4=C(C)C(C5=C(C)C=C(OCC[C@H](O)CO)C=C5C)=CC=C4)=CC=C13

Molecular Formula

C32H35NaO7

Molecular Weight

554.61

References & Citations

[1]Tanaka, H., et al., (2014) . Novel GPR40 agonist AS2575959 exhibits glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion. Life sciences, 94 (2), 115-121.