AS2575959 (sodium)
AS2575959 (sodium) is an agonist of GPR40. AS2575959 (sodium) can enhance glucose metabolism and has synergic effect with Sitagliptin (HY-13749) on insulin as well as incretin secretion. AS2575959 (sodium) can be studied in research on type 2 diabetes[1].
Product Specifications
CAS Number
[1616871-34-1]
UNSPSC
12352005
Target
Free Fatty Acid Receptor
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
O=C(O[Na])C[C@@H]1C2(CC2)OC3=CC(OCC4=C(C)C(C5=C(C)C=C(OCC[C@H](O)CO)C=C5C)=CC=C4)=CC=C13
Molecular Formula
C32H35NaO7
Molecular Weight
554.61
References & Citations
[1]Tanaka, H., et al., (2014) . Novel GPR40 agonist AS2575959 exhibits glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion. Life sciences, 94 (2), 115-121.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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