ONO 2050297
ONO 2050297 (Compound 19) is a selective Cysteinyl leukotriene (CysLT) antagonist with IC50s of 17 and 0.87 nM for CysLT1 and CysLT2, respectively. ONO 2050297 can be used for bronchial asthma research[1].
Product Specifications
CAS Number
847655-65-6
UNSPSC
12352005
Target
Leukotriene Receptor
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
O=C([C@H]1OC2=C(NC(C3=CC=C(OCCCCC4=CC=CC=C4)C=C3)=O)C=CC=C2N(CCCC(O)=O)C1)O
Molecular Formula
C30H32N2O7
Molecular Weight
532.58
References & Citations
[1]Itadani S, et al. Discovery of Highly Potent Dual CysLT1 and CysLT2 Antagonist. ACS Med Chem Lett. 2014 Oct 6;5 (11) :1230-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTC4/CysLT2; LTD4/CysLT1
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