JNJ-5234801
JNJ-5234801 is an orally active anxiolytic that targets the 5-HT2 receptor. JNJ-5234801 increases water intake and reduces alcohol preference in rats. JNJ-5234801 could be used in studies on anxiety and alcoholism[1].
Product Specifications
CAS Number
426227-09-0
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(NC1=CC=CC=C1)CC2CCN(C(C3=CC=CC(C#CC4=NC=CC=C4)=C3)=O)CC2
Molecular Formula
C27H25N3O2
Molecular Weight
423.51
References & Citations
[1]Rezvani AH, et al. Effects of atypical anxiolytic N-phenyl-2-[1-[3- (2-pyridinylethynyl) benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats. Alcohol Clin Exp Res. 2007 Jan;31 (1) :57-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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