JNJ-5234801

JNJ-5234801 is an orally active anxiolytic that targets the 5-HT2 receptor. JNJ-5234801 increases water intake and reduces alcohol preference in rats. JNJ-5234801 could be used in studies on anxiety and alcoholism[1].

Product Specifications

CAS Number

[426227-09-0]

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(NC1=CC=CC=C1)CC2CCN(C(C3=CC=CC(C#CC4=NC=CC=C4)=C3)=O)CC2

Molecular Formula

C27H25N3O2

Molecular Weight

423.51

References & Citations

[1]Rezvani AH, et al. Effects of atypical anxiolytic N-phenyl-2-[1-[3- (2-pyridinylethynyl) benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats. Alcohol Clin Exp Res. 2007 Jan;31 (1) :57-63.