AV-4025 (hydrochloride)
AV-4025 hydrochloride (Compound 13a) is an orally active NS5A inhibitor. AV-4025 hydrochloride is active against the HCV replicon GT1b (EC50 = 0.003 nM) . AV-4025 hydrochloride can be used for research on hepatitis C infection[1].
Product Specifications
CAS Number
[1380290-35-6]
UNSPSC
12352005
Target
HCV Protease; Influenza Virus
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C([C@@H](NC(OC)=O)C(C)C)N1CCC[C@H]1C(N2)=NC=C2C3=CC=C(C#CC#CC4=CN=C([C@H]5N(C([C@H](C(C)C)NC(OC)=O)=O)CCC5)N4)C=C3.Cl.Cl
Molecular Formula
C38H48Cl2N8O6
Molecular Weight
783.74
References & Citations
[1]Ivachtchenko AV, et al. Discovery of novel highly potent hepatitis C virus NS5A inhibitor (AV4025) . J Med Chem. 2014 Sep 25;57 (18) :7716-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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