Bay-02752
Bay-02752 (Bay o 2752) is a lipid-lowering agent. Bay-02752 inhibits acyl-CoA activity in liver microsomes (IC50 = 0.95 μg/mL) . Bay-02752 inhibits intestinal cholesterol absorption in rats. Bay-02752 inhibits gallstone formation in hamsters[1][2].
Product Specifications
CAS Number
78991-74-9
Product Name Alternative
Bay o 2752
UNSPSC
12352005
Target
Acyltransferase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C(N1C(C)CC2=C1C=CC=C2)NCCCCCCCCCCCNC(N3C(C)CC4=C3C=CC=C4)=O
Molecular Formula
C31H44N4O2
Molecular Weight
504.71
References & Citations
[1]AKritchevsky D, et al. Influence of N, N'- (1,11-undecandiyl) bis (2,3-dihydro-2-methyl-1H-indole-1-carboxamide) (BAY 02752) on gallstone formation and regression in hamsters. Pharmacol Res Commun. 1987 Oct;19 (10) :679-84.|[2]Harnett KM, et al.. Effects of Bay o 2752, a hypocholesterolemic agent, on intestinal taurocholate absorption and cholesterol esterification. J Pharmacol Exp Ther. 1989 Nov;251 (2) :502-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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