PF 1022A (Standard)

PF 1022A (Standard) is the analytical standard of PF 1022A. This product is intended for research and analytical applications. PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research[1][2][3].

Product Specifications

CAS Number

[133413-70-4]

UNSPSC

12352005

Target

Parasite; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=C(N([C@H](C(O[C@](C(N([C@H](C(O[C@H](CC1=CC=CC=C1)C2=O)=O)CC(C)C)C)=O)([H])C)=O)CC(C)C)C)[C@H](OC([C@@H](N(C([C@H](OC([C@](N2C)([H])CC(C)C)=O)C)=O)C)CC(C)C)=O)CC3=CC=CC=C3

Molecular Formula

C52H76N4O12

Molecular Weight

949.18

References & Citations

[1]Sasaki T, et al. A new anthelmintic cyclodepsipeptide, PF1022A. J Antibiot (Tokyo) . 1992 May;45 (5) :692-7.|[2]Dornetshuber R, et al. Effects of the anthelmintic drug PF1022A on mammalian tissue and cells. Biochem Pharmacol. 2009 Apr 15;77 (8) :1437-44.|[3]Nwosu U, et al. Efficacy of the cyclooctadepsipeptide PF1022A against Heligmosomoides bakeri in vitro and in vivo. Parasitology. 2011 Aug;138 (9) :1193-201.