Bempedoic acid (Standard)

Bempedoic acid (Standard) is the analytical standard of Bempedoic acid. This product is intended for research and analytical applications. Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor[1]. Bempedoic acid (ETC-1002) activates AMPK[2].

Product Specifications

CAS Number

[738606-46-7]

Product Name Alternative

ETC-1002 (Standard) ; ESP-55016 (Standard)

UNSPSC

12352211

Target

AMPK; ATP Citrate Lyase; Reference Standards

Related Pathways

Epigenetics; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR

Field of Research

Metabolic Disease

Smiles

O=C(O)C(C)(C)CCCCCC(O)CCCCCC(C)(C)C(O)=O

Molecular Formula

C19H36O5

Molecular Weight

344.49

References & Citations

[1]Pinkosky SL, et al. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan;54 (1) :134-51.|[2]Filippov S, et al. ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK. J Lipid Res. 2013 Aug;54 (8) :2095-108.|[3]Pinkosky SL, et al. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan;54 (1) :134-51.|[4]Filippov S, et al. ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK. J Lipid Res. 2013 Aug;54 (8) :2095-108.