DC07090
DC07090 is a potent, reversible and competitive non-peptidyl human enterovirus 71 3C protease inhibitor with an IC50 and a Ki value for 21.72 μM and 23.29 μM. DC07090 could also inhibit coxsackievirus A16 (CVA16) replication with an EC50 value of 27.76 μM[1].
Product Specifications
CAS Number
879070-72-1
UNSPSC
12352005
Target
Enterovirus
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
C1(C(C=C2)=CC=C2NCC3=NC=CC=C3)=NC(N=CC=C4)=C4O1
Molecular Formula
C18H14N4O
Molecular Weight
302.33
References & Citations
[1]Ma GH, et al. Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening. Eur J Med Chem. 2016 Nov 29;124:981-991.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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