PD 131628
PD 131628 is an antimicrobial agent and active PD 131112 metabolite. PD 131628 is two- to four-fold more active than Ciprofloxacin (HY-B0356), inhibiting all strains of Staphylococcus aureus and Streptococcus pneumoniae. PD 131628 is very active against Neisseria spp., Haemophilus influenzae and Moraxella catarrhalis, with MIC90s ranging from 0.004 to 0.008 mg/L[1].
Product Specifications
CAS Number
[127967-03-7]
UNSPSC
12352005
Target
Bacterial; Drug Metabolite
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(O)C1=CN(C2=C(C1=O)C=C(C(N3C[C@H](CC3)N)=N2)F)C4CC4
Molecular Formula
C16H17FN4O3
Molecular Weight
332.33
References & Citations
[1]Cooper MA, et al. In-vitro activity of PD 131628, a new quinolone antimicrobial agent. J Antimicrob Chemother. 1992 May;29 (5) :519-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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