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PD 131628

PD 131628 is an antimicrobial agent and active PD 131112 metabolite. PD 131628 is two- to four-fold more active than Ciprofloxacin , inhibiting all strains of Staphylococcus aureus and Streptococcus pneumoniae. PD 131628 is very active against Neisseria spp., Haemophilus influenzae and Moraxella catarrhalis, with MIC90s ranging from 0.004 to 0.008 mg/L[1].

Product Specifications

CAS Number

127967-03-7

UNSPSC

12352005

Target

Bacterial; Drug Metabolite

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(O)C1=CN(C2=C(C1=O)C=C(C(N3C[C@H](CC3)N)=N2)F)C4CC4

Molecular Formula

C16H17FN4O3

Molecular Weight

332.33

References & Citations

[1]Cooper MA, et al. In-vitro activity of PD 131628, a new quinolone antimicrobial agent. J Antimicrob Chemother. 1992 May;29 (5) :519-27.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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