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GR-175737

GR 175737 is a partial histamine H3 receptor agonist, with an EC50 of 7.8 nM. GR 175737 can be used in the research of inflammatory diseases[1].

Product Specifications

CAS Number

176860-26-7

UNSPSC

12352005

Target

Histamine Receptor

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Field of Research

Inflammation/Immunology

Smiles

ClC1=CC=C(C=C1)CC2=NOC(CCC3=CN=CN3)=N2

Molecular Formula

C14H13ClN4O

Molecular Weight

288.73

References & Citations

[1]Soudijn W, et al. Structure–activity relationships of inverse agonists for G‐protein‐coupled receptors. Medicinal research reviews, 2005, 25 (4) : 398-426.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

H3 Receptor

Frequently Asked Questions

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