Alloxazine (Standard)
Alloxazine (Standard) is the analytical standard of Alloxazine. This product is intended for research and analytical applications. Alloxazine is a selective A2b antagonist. Alloxazine completely block 5’N-Ethylcarboxamido adenosine (NECA) -mediated cyclic AMP accumulation with an IC50 of 2.9 μM. Alloxazine can be used for the research of cancer[1][2].
Product Specifications
CAS Number
[490-59-5]
UNSPSC
12352100
Target
Adenosine Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Cancer
Smiles
O=C(N1)N=C2NC3=CC=CC=C3N=C2C1=O
Molecular Formula
C10H6N4O2
Molecular Weight
214.18
References & Citations
[1]Brackett LE, Daly JW. Functional characterization of the A2b adenosine receptor in NIH 3T3 fibroblasts. Biochem Pharmacol. 1994 Mar 2;47 (5) :801-14.|[2]Shin HK, et al. Role of adenosine A (2B) receptors in vasodilation of rat pial artery and cerebral blood flow autoregulation. Am J Physiol Heart Circ Physiol. 2000 Feb;278 (2) :H339-44.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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