(2S,3S) -Zenidolol (hydrochloride)
(2S,3S) -Zenidolol ((2S,3S) -ICI-118551) hydrochloride is a β2-adrenergic receptor (β2AR) antagonist with pKi values for β1AR and β2AR of 7.51 and 9.27 respectively. (2S,3S) -Zenidolol hydrochloride can be used in the research of heart failure, ischemic heart disease and hypertension[1].
Product Specifications
CAS Number
[1236034-74-4]
Product Name Alternative
(2S,3S) -ICI-118551 (hydrochloride)
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cardiovascular Disease
Smiles
CC(C)N[C@@H](C)[C@H](O)COC1=C2C(CCC2)=C(C=C1)C.Cl
Molecular Formula
C17H28ClNO2
Molecular Weight
313.86
References & Citations
[1]Baker JR, et al. An efficient asymmetric synthesis of the potent beta-blocker ICI-118,551 allows the determination of enantiomer dependency on biological activity. Chem Commun (Camb) . 2010 Jun 14;46 (22) :3953-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor
Curated Selection
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