Setanaxib (Standard)
Setanaxib (Standard) is the analytical standard of Setanaxib. This product is intended for research and analytical applications. Setanaxib (GKT137831) is a selective NADPH oxidase (NOX1/4) inhibitor with Kis of 140 and 110 nM, respectively.
Product Specifications
CAS Number
1218942-37-0
UNSPSC
12352100
Target
Ferroptosis; NADPH Oxidase; Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
O=C1N(C2=CC=CC=C2Cl)NC(C1=C(C3=CC=CC(N(C)C)=C3)N4C)=CC4=O
Molecular Formula
C21H19ClN4O2
Molecular Weight
394.85
References & Citations
[1]Aoyama T, et al. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent. Hepatology. 2012 Dec;56 (6) :2316-27.|[2]Green DE, et al. The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation. Am J Respir Cell Mol Biol. 2012 Nov;47 (5) :718-26.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![ZNF365 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4E9]](https://cdn.genprice.uk/products/937/6868c385994c49e6dc3f935b/imageurl/ta800133am.webp)
TA800133AM 100 µL
ZNF365 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4E9]
Sign In for Pricing
View Details 
16540-AAT 200 µg
IFluor® 555 goat anti-mouse IgG (H+L) *Cross Adsorbed*
Sign In for Pricing
View Details 
TRC-F692117-5MG 5 mg
2-(2-Formamidothiazol-4-yl)acetic Acid-13C,15N2
Sign In for Pricing
View Details 
LY422529 100 µg
SH3KBP1 (NM_001024666) Human Over-expression Lysate
Sign In for Pricing
View Details