Setanaxib (Standard)
Setanaxib (Standard) is the analytical standard of Setanaxib. This product is intended for research and analytical applications. Setanaxib (GKT137831) is a selective NADPH oxidase (NOX1/4) inhibitor with Kis of 140 and 110 nM, respectively.
Product Specifications
UNSPSC
12352100
Target
Ferroptosis; NADPH Oxidase; Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
O=C1N(C2=CC=CC=C2Cl)NC(C1=C(C3=CC=CC(N(C)C)=C3)N4C)=CC4=O
Molecular Formula
C21H19ClN4O2
Molecular Weight
394.85
References & Citations
[1]Aoyama T, et al. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent. Hepatology. 2012 Dec;56 (6) :2316-27.|[2]Green DE, et al. The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation. Am J Respir Cell Mol Biol. 2012 Nov;47 (5) :718-26.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12298R/
Scientific Category
Reference Standards
CAS Number
[1218942-37-0]
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Human Monoclonal xCT Antibody (Agilvax Patent Anti-Slc7A11) [Janelia Fluor 635]](https://cdn.genprice.uk/genprice/genprice2.png)
NBP3-28188JF635 0.1 mL
Human Monoclonal xCT Antibody (Agilvax Patent Anti-Slc7A11) [Janelia Fluor 635]
Ask
View Details 
MBS6244878-01 0.1 mL
GABA Receptor A, alpha 1 (Gamma-aminobutyric Acid Receptor Type A alpha 1 Subunit, GABRA) (MaxLight 405)
Ask
View Details MBS6244878-02 5x 0.1 mL
GABA Receptor A, alpha 1 (Gamma-aminobutyric Acid Receptor Type A alpha 1 Subunit, GABRA) (MaxLight 405)
Ask
View Details 