Setanaxib (Standard)
Setanaxib (Standard) is the analytical standard of Setanaxib. This product is intended for research and analytical applications. Setanaxib (GKT137831) is a selective NADPH oxidase (NOX1/4) inhibitor with Kis of 140 and 110 nM, respectively.
Product Specifications
CAS Number
1218942-37-0
UNSPSC
12352100
Target
Ferroptosis; NADPH Oxidase; Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
O=C1N(C2=CC=CC=C2Cl)NC(C1=C(C3=CC=CC(N(C)C)=C3)N4C)=CC4=O
Molecular Formula
C21H19ClN4O2
Molecular Weight
394.85
References & Citations
[1]Aoyama T, et al. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent. Hepatology. 2012 Dec;56 (6) :2316-27.|[2]Green DE, et al. The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation. Am J Respir Cell Mol Biol. 2012 Nov;47 (5) :718-26.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
FCSTM25-18 1 Kit
Human Tumor Biomarker Premixed Kit Luminex Performance Assay
Sign In for Pricing
View Details 35868066 1.0 µg DNA
P2RY12 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
LV755412 1.0 µg DNA
USP9YP16 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details