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IM-12 (Standard)

IM-12 (Standard) is the analytical standard of IM-12. This product is intended for research and analytical applications. IM-12 is an inhibitor of GSK-3β, with an IC50 of 53 nM, and also enhances Wnt signalling.

Product Specifications

CAS Number

1129669-05-1

UNSPSC

12352100

Target

GSK-3; Reference Standards; Wnt

Related Pathways

Others; PI3K/Akt/mTOR; Stem Cell/Wnt

Field of Research

Cancer

Smiles

O=C(C(NCCC1=CC=C(F)C=C1)=C2C3=C(C)NC4=C3C=CC=C4)N(C)C2=O

Molecular Formula

C22H20FN3O2

Molecular Weight

377.41

References & Citations

[1]Schmole AC, et al. Novel indolylmaleimide acts as GSK-3beta inhibitor in human neural progenitor cells. Bioorg Med Chem. 2010 Sep 15;18 (18) :6785-95.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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