IM-12 (Standard)
IM-12 (Standard) is the analytical standard of IM-12. This product is intended for research and analytical applications. IM-12 is an inhibitor of GSK-3β, with an IC50 of 53 nM, and also enhances Wnt signalling.
Product Specifications
CAS Number
[1129669-05-1]
UNSPSC
12352100
Target
GSK-3; Reference Standards; Wnt
Related Pathways
Others; PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(C(NCCC1=CC=C(F)C=C1)=C2C3=C(C)NC4=C3C=CC=C4)N(C)C2=O
Molecular Formula
C22H20FN3O2
Molecular Weight
377.41
References & Citations
[1]Schmole AC, et al. Novel indolylmaleimide acts as GSK-3beta inhibitor in human neural progenitor cells. Bioorg Med Chem. 2010 Sep 15;18 (18) :6785-95.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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