Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CHMFL-KIT-031

CHMFL-KIT-031 is a highly selective KIT V559D inhibitor, with an IC50 of 28 nM. CHMFL-KIT-031 potently affects KIT V559D mutant’s phosphorylation at Y703/719/823 sites. CHMFL-KIT-031 inhibits the tumor growth in BaF3-TEL-KIT-V559D cell inoculated mouse model[1].

Product Specifications

UNSPSC

12352005

Target

C-Kit

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(NCC(NC1=CC2=C(C=C1)C(/C=C/C3=NC=CC=C3)=NN2)=O)C4=CC(OC)=C(OC)C(OC)=C4

Molecular Formula

C26H25N5O5

Molecular Weight

487.51

References & Citations

[1]Yu K, et al. Discovery of a highly selective KIT kinase primary V559D mutant inhibitor for gastrointestinal stromal tumors (GISTs) . Oncotarget. 2017 Nov 15;8 (67) :111110-111118.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NIPSNAP3B Antibody
MBS9401556-01 0.1 mL

NIPSNAP3B Antibody

Ask
View Details
NIPSNAP3B Antibody
MBS9401556-02 5x 0.1 mL

NIPSNAP3B Antibody

Ask
View Details
Rabbit Polyclonal DRIL1 Antibody [DyLight 680]
NBP2-98981FR 0.1 mL

Rabbit Polyclonal DRIL1 Antibody [DyLight 680]

Ask
View Details
1-o-Tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
228910-01 100 mg

1-o-Tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Ask
View Details
1-o-Tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
228910-02 250 mg

1-o-Tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Ask
View Details
1-o-Tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
228910-03 1 g

1-o-Tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Ask
View Details