Inh2-B1
Inh2-B1 is a Ser/Thr protein kinase (STK1) inhibitor. Inh2-B1 specifically inhibits STK1 activity by directly binding to its ATP-binding catalytic domain. Inh2-B1 down-regulates cell wall hydrolase genes and disrupts the biofilm formation of Methicillin-resistant Staphylococcus aureus (MRSA) clearly[1].
Product Specifications
CAS Number
[690216-38-7]
UNSPSC
12352005
Target
Bacterial; Ser/Thr Kinase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(C1=CC(N2C(N3)=C(C(NC4=CC=CC=C4)=O)SC2=S)=C(C=C1)C3=O)OC
Molecular Formula
C19H13N3O4S2
Molecular Weight
411.45
References & Citations
[1]Kant S, et al. A novel STK1-targeted small-molecule as an "antibiotic resistance breaker" against multidrug-resistant Staphylococcus aureus. Sci Rep. 2017 Jul 11;7 (1) :5067.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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