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Inh2-B1

Inh2-B1 is a Ser/Thr protein kinase (STK1) inhibitor. Inh2-B1 specifically inhibits STK1 activity by directly binding to its ATP-binding catalytic domain. Inh2-B1 down-regulates cell wall hydrolase genes and disrupts the biofilm formation of Methicillin-resistant Staphylococcus aureus (MRSA) clearly[1].

Product Specifications

CAS Number

690216-38-7

UNSPSC

12352005

Target

Bacterial; Ser/Thr Kinase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=C(C1=CC(N2C(N3)=C(C(NC4=CC=CC=C4)=O)SC2=S)=C(C=C1)C3=O)OC

Molecular Formula

C19H13N3O4S2

Molecular Weight

411.45

References & Citations

[1]Kant S, et al. A novel STK1-targeted small-molecule as an "antibiotic resistance breaker" against multidrug-resistant Staphylococcus aureus. Sci Rep. 2017 Jul 11;7 (1) :5067.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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